SAGE Library Construction Group
The SAGE Library Construction Group is a part of Canada's Michael Smith Genome Sciences Centre. They are responsible for turning the mouse tissue samples into SAGE libraries for sequencing.
Marco Marra, Ph.D.
Director, Canada's Michael Smith Genome Sciences Centre
Director of the British Columbia Cancer Agency Genome Sciences Centre.
Dr. Marra is also the Director of the Genome BC Sequencing and Mapping
Platform. He holds the appointments of Senior Scientist at the British
Columbia Cancer Agency, Associate Member of the Biotechnology
Laboratory at the University of British Columbia, Associate Professor
of Medical Genetics at the University of British Columbia and Adjunct
Professor of Molecular Biology and Biochemistry at Simon Fraser
University. Dr. Marra has been involved for many years in the
development and application of efficient high throughput genomics
strategies, with special emphasis on large-scale genome mapping and DNA
sequencing. Accomplishments to date have included construction of
whole-genome sequence ready maps, assembled from fingerprinted BAC
clones, for the human genome, and the genomes of Caenorhabditis
briggsae, Arabidposis thaliana, Cryptococcus neoformans and most
recently the laboratory mouse and rat. Maps for the bovine and salmon
genomes are underway. In addition to whole-genome fingerprint map
construction, large-scale high throughput Expressed Sequence Tags (EST)
analysis and full-length cDNA sequencing has been used to construct
publicly accessible gene databases for both human and mouse. Current
activities include the development and application of large-scale
high-throughput gene expression assays to study cancer and development.
Serial Analysis of Gene Expression (SAGE) has been used extensively by
Dr. Marra's groups at Washington University Genome Sequencing Center in
St. Louis and at the British Columbia Cancer Agency Genome Sciences
Centre to examine mRNA expression changes of relevance to cancer,
ageing and virulence of fungal pathogens.
Martin Hirst, Ph.D.
Research Associate
Jaswinder Khattra
Graduate Student
Yongjun Zhao, M.Sc., DVM
Assistant Production Coordinator, SAGE Technologies
Susanna Chan, B.Sc.
Assistant Production Coordinator, Affymetrix Technologies
Adrian Ally, B.Sc.
Expression Technologist
Jennifer Asano
Expression Technologist
Sean Couglin, B.Sc.
Expression Technologist
Noreen Dhalla, B.Sc.
Expression Technologist
Stephanie Lee, B.Sc.
Expression Technologist
Kevin Ma, B.Sc.
Expression Technologist
Helen McDonald, M.Sc.
Research Assistant
Pawan Pandoh, B.Sc.
Expression Technologist
Anna-Liisa Prabhu, B.Sc.
Expression Technologist
Danne Sa, B.Sc.
Expression Technologist
Angela Tam, B.Sc.
Expression Technologist