SAGE Library Construction and ChIP development Group

The SAGE Library Construction Group is a part of Canada's Michael Smith Genome Sciences Centre. They are responsible for turning the mouse tissue samples into SAGE libraries for sequencing. Activities also include development of ChIP - SAGE technology.

Marco Marra, Ph.D.

Director, Canada's Michael Smith Genome Sciences Centre

Director of the British Columbia Cancer Agency Genome Sciences Centre. Dr. Marra is also the Director of the Genome BC Sequencing and Mapping Platform. He holds the appointments of Senior Scientist at the British Columbia Cancer Agency, Associate Member of the Biotechnology Laboratory at the University of British Columbia, Associate Professor of Medical Genetics at the University of British Columbia and Adjunct Professor of Molecular Biology and Biochemistry at Simon Fraser University. Dr. Marra has been involved for many years in the development and application of efficient high throughput genomics strategies, with special emphasis on large-scale genome mapping and DNA sequencing. Accomplishments to date have included construction of whole-genome sequence ready maps, assembled from fingerprinted BAC clones, for the human genome, and the genomes of Caenorhabditis briggsae, Arabidposis thaliana, Cryptococcus neoformans and most recently the laboratory mouse and rat. Maps for the bovine and salmon genomes are underway. In addition to whole-genome fingerprint map construction, large-scale high throughput Expressed Sequence Tags (EST) analysis and full-length cDNA sequencing has been used to construct publicly accessible gene databases for both human and mouse. Current activities include the development and application of large-scale high-throughput gene expression assays to study cancer and development. Serial Analysis of Gene Expression (SAGE) has been used extensively by Dr. Marra's groups at Washington University Genome Sequencing Center in St. Louis and at the British Columbia Cancer Agency Genome Sciences Centre to examine mRNA expression changes of relevance to cancer, ageing and virulence of fungal pathogens.

 

Martin Hirst, Ph.D.

Staff Scientist, Functional Genomics Group Leader

Angela Tam, B.Sc., ChIP development

Expression Technologist

Yongjun Zhao, M.Sc., DVM

Assistant Production Coordinator, SAGE Technologies

Susanna Chan, B.Sc.

Assistant Production Coordinator, Affymetrix Technologies

Adrian Ally, B.Sc.

Expression Technologist

Jennifer Asano

Expression Technologist

Sean Couglin, B.Sc.

Expression Technologist

Noreen Dhalla, B.Sc.

Expression Technologist

Stephanie Lee, B.Sc.

Expression Technologist

Kevin Ma, B.Sc.

Expression Technologist

Helen McDonald, M.Sc.

Research Assistant

Pawan Pandoh, B.Sc.

Expression Technologist

Anna-Liisa Prabhu, B.Sc.

Expression Technologist

Danne Sa, B.Sc.

Expression Technologist