Pamela Hoodless Lab

hoodless team photo

The Hoodless laboratory is primarily interested in the early stages of mammalian development, from one cell through to gastrulation, and organogenesis, in particular, focusing on the heart and gut.

In general, the laboratory is interested in early events in mammalian development and the signaling pathways that regulate these processes. The laboratory's main interests revolve around node formation and function in the early mouse gastrula, early endoderm formation and patterning, and cardiac patterning.

Pamela Hoodless, Ph.D.

Project Co-Leader

Dr. Hoodless is a Senior Scientist in the Terry Fox Laboratory at the BC Cancer Agency with a cross-appointment to the Department of Medical Genetics at University of British Columbia.

Rebecca Cullum, B.Sc.

Research Assistant II

Rebecca has been a part of the MouseAtlas and MORGEN projects since late 2003. Her ongoing interest in understanding the transcriptional networks that underlie the development of both the liver and the heart means she has been involved in almost every area of this project. This includes tissue collection, data analysis, experimentation with ChIP and ChIP-seq and integrating all of the information on the genomic level.

 

Juan Hou, Ph.D.

Postdoctoral Fellow

Juan Hou joined Hoodless Lab in early 2004. She is interested in early event of mammalian development, especially the formation, the lineage and functional properties of the mouse gastrula organizer. She is involved in node-relative tissue collection and those libraries analysis.

Pavle Vrljicak, M.Sc.

Graduate Student

Pavle Vrljicak joined the Hoodless lab as a PhD student in late 2003 after completing his MSc at McGill University, where he worked on kidney development. He is interested in the role of transcription factors in organogenesis. He is currently involved in tissue collection and analysis of the early kidney and lung libraries, as well as the analysis and validation of the heart libraries.

Elizabeth Wederell, Ph.D.

Postdoctoral Fellow

Elizabeth recently joined the Hoodless team in January 2006 after completing a Postdoctoral Fellowship in the Cancer Biology Department at the BCCRC. She is investigating factors involved in endothelial-to-mesenchymal transformation (EMT) in heart development, and collecting tissues from various developmental stages for SAGE library creation.

Sam Lee, M.Sc.

Graduate Student

Sam is a PhD candidate in the Hoodless lab and is primarily working on the liver. For the MORGEN project he is focusing on collecting liver precursor cells for the development of SAGE libraries.